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The GLP-1 receptor is a type of cell surface receptor that binds to GLP-1, triggering a signaling cascade that leads to various effects, including the stimulation of insulin secretion, the inhibition of gastric emptying, and the promotion of satiety

EFSA Journal, 23 (5), e9371

Clinical context: The SURMOUNT-1 trial showed tirzepatide produced an average 22.5% body weight loss over 72 weeks

The two strongest signals for preserving muscle are: adequate protein intake resistance training Without those signals, the body may break down both fat and muscle for energy during weight loss

Prescriptions are written by independent licensed clinicians at affiliated medical groups, including CareValidate Health, Usable Health PC, and CareGLP Affiliated P.C.s

Long-term safety data still pending