Klatsky AL, Morton C, Udaltsova N, Friedman GD (2006)
As peptides become more popular in the development of new therapeutics, it is increasingly important to quickly optimize the synthetic and cleavage processes by isolating and identifying both the target peptide and its related impurities
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The free GHK tripeptide was first isolated from human plasma in 1973 by Loren Pickart, and the copper-bound form has been studied since the 1980s as a regenerative-research reference compound.nnActive research areas include extracellular matrix gene expression, collagen and decorin regulation, matrix-metalloproteinase modulation, antioxidant pathway activity, and copper-mediated cell signalling
