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US FDA requires proper labeling and GMP compliance

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The potencies observed in cellular assays show that it is a potent agonist at the GIP receptor, but exhibits balanced activity across GLP-1 and Glucagon receptors

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It received FDA approval for the treatment of growth hormone deficiency in children (marketed as Geref Diagnostic) and was used clinically for years before being voluntarily withdrawn from the market for commercial reasons not safety concerns