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These modifications in metabolism pathways resulted in a substantial increase in the levels of 39 metabolites in acute COVID 19 patients compared to the R group such as phenylaniline, pyrimidodiazepine, xanthine, ascorbate, kynurenine, 5-hydroxykynurenine and others as outlined in Supplementary Figures 8A, B

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Division of Dermatology, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa ABSTRACT BACKGROUND: Glutathione (GSH) is the most abundant naturally occurring non-protein thiol that protects mammalian cells from oxidative stress