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doi: 10.1016/j.nbd.2009.02.009 44 ChenL

Oral treatment with the ghrelin receptor agonist HM01 attenuates Cachexia in mice bearing Colon-26 (C26) tumors

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The lethal dose threshold (LD1) was never achieved in animal safety studies meaning researchers could not identify a dose lethal to 1% of test subjects

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doi:10.2147/CE.S55944