Glucuronidation also contributes to ochratoxin A detoxification, so UGT variants may have an overlapping impact across several mycotoxins.[ref] Related article: Glucuronidation: UGT Genetic Variants, Detoxification, and Hormone Balance Patulin and glutathione-dependent pathways: Patulin, a mycotoxin most commonly found in moldy apples and apple juice, binds to thiol groups in glutathione, depleting this key intracellular antioxidant and triggering oxidative stress and mitochondrial dysfunction
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[1] MOTS-c is a novel peptide derived from mitochondrial DNA, which encodes 37 genes, including 22 tRNAs, 2 rRNAs, and 13 mRNAs
No nutritional counseling or weight-loss program was provided as part of the study
