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Over the past few years, numerous docking studies and molecular dynamic simulations were performed in an attempt to elucidate the binding modes of tyrosinase inhibitors

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With every trial, weve felt a step closer to diverting the surging immense CV and renal risk in the DKD population

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In cancer cells, TrxR1/2 inhibition by Hdy-7 induces cytotoxic autophagy through elevated ROS and TFEB activation, which can be reversed by antioxidants or p53 knockdown, illustrating the redox sensitivity of this pathway

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