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Vasodilation is achieved by activating endothelial nitric oxide synthase (eNOS) and increasing nitric oxide (NO) production via the cAMP/PKA, AMPK, and PI 3 K/Akt signaling pathways [17]

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The FOXO4 factor is considered to regulate various cell pathways, including insulin signaling, cell cycle progression, and other functions that regulate growth and differentiation

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