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Description

Melanotan II is a synthetic analogue of the peptide hormone -melanocyte-stimulating hormone (-MSH) that stimulates melanogenesis to facilitate tanning

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(Lond.) 33 , 956961 (2009)

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In this context, it has been observed that the inhibition of PARP activity through its cleavage can destabilize replication forks, leading to replication stress and potentially excessive entry into the S-phase as cells attempt to compensate for incomplete DNA synthesis [60]

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