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Furthermore, when combined with anti-PD1 or anti-CTLA4 antibodies, CB-839 promotes the infiltration of effector T cells into tumors and upregulates IFN-associated gene expression, thereby enhancing the antitumor activity of these checkpoint inhibitors [199]

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That was a nonnegotiable. Now its not a necessity anymore. This story was first published July 8, 2024, by Stateline, an initiative of The Pew Charitable Trusts.

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