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The anti-apoptotic activity of TB-500 may involve the reduction of early cell death initiation signals and activation of the survival kinase Akt through complex formation with PINCH and integrin-linked kinase

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The positive correlation between HGF and SC marker gene expression detected by single-cell qRTPCR analysis, supports the notion that the SC population is enriched in HGF/c-MET-positive cells (Fig

weight loss of 10% and above is associated with improved cardiovascular outcomes

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