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What the Preclinical Research Suggests: Laboratory studies using animal models have examined several biological processes: Tendon and Ligament Processes: Rodent studies have demonstrated effects in Achilles tendon injury models, with treated animals showing differences compared to controls in controlled laboratory conditions

For example, PEPCK and G6P activities are increased in obese individuals (Ropelle et al., 2009

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The consistent findingsthat phytochemicals like flavonoids, phenolic acids, and polysaccharides can mitigate MASLD by regulating lipid metabolism, oxidative stress, and inflammationvalidate the zebrafish as a powerful tool for bridging the gap between the discovery of natural compounds and the development of novel, mechanism-informed treatment strategies for liver disease

Clark, W.F., et al., Fish oil in lupus nephritis: clinical findings and methodological implications