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ROS can either (i) promote protumorigenic signaling supporting the proliferation and survival of cancer cells or (ii) conversely promote antitumorigenic signaling and oxidative stress-induced cancer cell death (Reczek and Chandel 2017)

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Additional file 1: Figure S1B)

On EDD4, the upper part of the eggs was opened in a circular shape with a diameter of 12 cm, sealed with a plaster, and placed back into the incubator