can semaglutide damage your pancreas Suspected drug-induced pancreatitis was rare but more common in patients taking GLP-1 agonists than sulfonylureas, a recent analysis of a VA database finds GLP-1s and GI Side Effects:

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Cardiovascular Considerations Most people notice a slight bump in resting heart rate when starting GLP-1 medications

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As of early 2025, the FDA had received more than 455 adverse event reports involving compounded semaglutide and more than 320 involving compounded tirzepatide figures that the agency now cites as active justification for enforcement