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Recent trial data demonstrate that these benefits extend to individuals without diabetes, underscoring their role as cardiometabolic therapies rather than purely glucose-lowering medications [50, 51]

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Funding This study was supported by grants from the Scientific Research Foundation of the Ministry of Education of China (Grant No.2021JH019) and Scientific Research Foundation of Postdoctoral Department of Heilongjiang Province (Grant No.LBH-Q21025)

MK-677 doesnt affect those hormones but does impair insulin sensitivity

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