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The findings may sound familiar to those who follow news about GLP-1s

Eid RA, Zaki MSA, Alaa Eldeen M, Alshehri MM, Shati AA, El-Kott AF

This deep cold dramatically slows down any potential degradation processes, keeping the peptide in its most stable state for an extended period

While Ozempic and Wegovy contain semaglutide, Mounjaro contains tirzepatide and works on both GLP-1 and GIP receptors

Increased perfusion occurs within 5-10 minutes, via insulin action on three different receptors in the endothelium, including insulin receptors, IGF-I receptors, and the insulin/IGF-I hybrid receptors, and this occurs well before the increase in insulin-stimulated glucose disposal (~ 20-30 minutes) in muscle

This is in line with the data presented by Tong et al