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Key Factors That Affect Your Maintenance Dose Two practical points from pattern-based experience: first, patients with higher dietary fat intake often report more gastrointestinal upset during titration, so conservative progressions work better

Thyroiditis Thyroid dysfunction is the most common endocrinologic irAEs due to ICIs (45)

Similarly, avoid the very back of the fridge or the top shelf near the cooling vent, as these areas are prone to freezing