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At first glance, it may appear that the existence of a successful De Novo classification would lower the barriers to entry for competitors, much in the way that high-risk device categories see faster regulatory approval for follow-on products 16

7.4 Communication with Healthcare Providers Patients should be encouraged to maintain open lines of communication with their healthcare providers

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They are the kind of amino acids found in the liver and the kidneys

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Researchers employ the peptide in in vitro and ex vivo models to probe the signaling cascades that regulate dendritic spine density, synaptic connectivity, and long-term potentiation