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doi: 10.3390/jcm14176159
The disruption of Golgi zinc homeostasis, whether through zinc depletion or transporter dysfunction, leads to unstacking of cisternae, vesiculation and fragmentation of the Golgi, impairing vesicle trafficking and protein sorting 73,135
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10 After attainment of steady state following 4 days of oral administration of levocarnitine tablets (1,980 mg q12h) or oral solution (2,000 mg q12h) to 15 healthy male volunteers, the mean urinary excretion of levocarnitine during a single dosing interval (12h) was about 9% of the orally administered dose (uncorrected for endogenous urinary excretion)
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GLP-1 is a 30-amino acid peptide hormone produced by differential post-translational processing of the proglucagon precursor protein by prohormone convertase 1/3 (PCSK1) in intestinal L-cells and in neurons of the nucleus tractus solitarii (NTS) in the brainstem
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