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A 2024 study (Bharucha et al., Neurogastroenterology & Motility) found LES pressure decreased by an average of 4.2 mmHg in tirzepatide-treated patients compared to placebo, but with high individual variability

Acta 1864 , 23222329 (2017)

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Horm Metab Res 42:657662 Robinson E, Tate M, Lockhart S et al (2016) Metabolically-inactive glucagon-like peptide-1(936)amide confers selective protective actions against post-myocardial infarction remodelling

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