Vitamin B12 deficiency is a recognised nutritional complication following bariatric surgery, including gastric banding (laparoscopic adjustable gastric banding, LAGB)
consider ECG if clinically indicated Nutritional status : Assess current dietary intake, eating patterns, and screen for disordered eating behaviours Mental health evaluation : Screen for depression, anxiety, or other psychiatric comorbidities that may affect treatment adherence or outcomes Weight and metabolic parameters : Record baseline weight, BMI, waist circumference, and relevant blood tests (HbA1c, lipid profile, renal function) Pregnancy status : Exclude pregnancy and discuss contraception requirements (Wegovy is contraindicated in pregnancy) Treatment should begin with a dose of 0.25 mg once weekly, increasing every 4 weeks (0.5 mg, 1.0 mg, 1.7 mg) to reach the maintenance dose of 2.4 mg if tolerated
They may advise restarting at a lower dose to re-establish tolerance
Individuals who are allergic to Semaglutide GLP-1 or any of its components should not use the medication
In addition to NAION, there is also evidence to suggest GLP-1 drugs can worsen diabetic eye disease, also known as diabetic retinopathy
Benefits, Dosing, and Administration Protocols Research on Sermorelin has shown several benefits in laboratory and clinical studies