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research shows no additional benefit above 1 mg daily Important: Doses above 1 mg (1,000 mcg) daily showed no additional metabolic benefits in clinical research

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In a study from 1995, for example, researchers at a Parke-Davis facility in Ann Arbor, Michigan, administered the substance to rats and found that it helped protect the rodents colons from harsh chemicals administered into their intestines an hour later

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Instead, it is likely because of other taste-independent factors, such as post-oral "appetition" signals that mediate food preference via gut-brain nutrient signaling mechanisms [63]