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Metformin treatment (2.5 mM and 10 mM) significantly sensitised radiosensitive HCT116 cells to 1.8 Gy radiation, when compared to vehicle control ( Figure 1F ) (relative mean surviving fraction (SF) standard error of mean (SEM)

Additionally, Tianlongkechuanling (TL) mitigates fibrosis by reducing the expression of multiple arginine cycle enzymes, including arginase-1, CPS1, OTC, ASS1, OAT, ASL, and iNOS, helping to restore the balance between arginase and NO synthase pathways [140]

Thalassemia: Thalassemia carriers are asymptomatic or mildly symptomatic and do not require treatment