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doi: 10.12890/2020_001646 53 PolonikovA

This dependence on G6PD activity in activated T cells occurs despite the partially redundant contribution of other enzymes like isocitrate dehydrogenase and malate dehydrogenase to the overall production of cellular NADPH, which is needed for biosynthesis of immune effector molecules ( Figure 1A-3 )

FDA-approved GLP-1 receptor agonists include semaglutide (Wegovy, Ozempic), tirzepatide (Mounjaro, Zepbound), liraglutide (Saxenda, Victoza), dulaglutide (Trulicity), and exenatide (Byetta, Bydureon)

Tao et al., 2022

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