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Semaglutide, a GLP-1 receptor agonist originally developed for type 2 diabetes, has demonstrated significant weight loss results in clinical trials, with some participants losing up to 22% of body weight over 68 weeks

PMID: 33479187

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ENDOSCOPIC BARIATRIC AND METABOLIC THERAPIES Endoscopic bariatric and metabolic therapies are a promising alternative to traditional metabolic-bariatric surgery

Observational studies reporting vitamin D and micronutrient insufficiencies during prolonged GLP-1RA use [94, 95, 101] suggest that nutritional monitoring may be warranted, although the magnitude and causal pathways remain to be clarified