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Blood flow or nerve sensitivity in these spots might not be normal

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Clinical trial data from the SURMOUNT series shows these incidence rates: Nausea: approximately 20 percent of patients Diarrhea: approximately 16 percent of patients Vomiting: approximately 9 percent of patients Constipation: varies by dose level Decreased appetite: expected therapeutic effect Abdominal pain: less common but reported Most gastrointestinal side effects are mild to moderate and occur during the first few weeks of treatment or after dose increases

Overall, this study demonstrates the efficacy of TPMs off-label use in treating essential tremors [26]

Diffuse pigmentation of maxillary attached gingiva: four cases of the cultural practice of gingival tattoo

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