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Photoprotective and Antioxidant Signaling Consistent with MC1R engagement, MT-2 has been shown in in-vitro models to reduce UV-induced cyclobutane pyrimidine dimer (CPD) formation and attenuate reactive oxygen species (ROS) accumulation in melanocytes, paralleling the photoprotective signaling profile documented for MT-1 (Abdel-Malek et al., Cancer Research, 2005)

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[1] [4] Common adverse effects include gastrointestinal symptomsnausea, vomiting, diarrhea, constipation, and abdominal painwhich are generally dose-dependent and may diminish over time with continued use

However, this still leaves most individuals substantially below their starting weight

Genetic insights should be interpreted alongside clinical assessment by a qualified healthcare provider to inform more tailored treatment conversations