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Urologiia (2011) 27-8:303

Second, we excluded patients with prior suicidal ideation or suicide attempts to reduce confounding, but this prevented us from evaluating whether tirzepatide could reduce suicidality in that high-risk subset

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Specifically, it might be speculated that the interaction of IGF-1 analogs with their specific receptors might initiate a series of biochemical reactions via the PI3K pathway, posited as essential for cell proliferation and survival

2008;121(Pt 22):368392