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In its letter, the FDA explained that it considered information from compounders and other sources when reevaluating the tirzepatide decision but was ultimately not swayed by the data

To find out, Sanyal's group randomly assigned 98 obese adults to receive a higher or lower dose of the drug

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This shuts down transcription of TNF-alpha, IL-1beta, IL-6, IL-8, and other pro-inflammatory cytokines

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