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Soluble Uric Acid Triggers the NLRP3 Inflammasome in a Mitochondrial ROS-Dependent Manner In an attempt to address the mechanisms by which sUA promotes NLRP3 inflammasome activation, we analyzed mitochondrial ROS production by staining cells with the mitochondrial-targeting fluorescent probe MitoSOX 53

Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study

The study authors stress that the widely used drugs remain highly beneficial for many patients

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PMID: 21356520

Q : What is the exact nature of the purpose of Dr