Glutathione and glutaredoxinkey players in cellular redox homeostasis and signaling
The long-acting strategies of GLP-1 drugs (amino acid substitutions, fatty acid side chain modifications, Fc fusion proteins, PEGylation) described in the article are only a small part of the current long-acting strategies, which have actually been applied to other protein-peptide drugs as early as
First, the drug barely gets into milk
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PubMed Urva, S., Coskun, T., Loghin, C., Cui, X., Beebe, E., OFarrell, L.S., Briere, D.A., Sloop, K.W., Benson, C.T., Aubry, A., & Haupt, A