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To address potential confounding inherent in observational studies, we employed a drug-target Mendelian randomization framework

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Their findings are based on data for 20,146 adults (average age 65

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DNA damage, oxidative stress, and chronic inflammation are all directly caused by this inadequate immune response (36)

The aforementioned activation may consequently result in the release of substance P, neurokinin A, or calcitonin gene-related peptide (CGRP) [16]