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A deficiency of the enzyme needed to metabolize cysteine c

Limit or avoid caffeine (coffee, tea, energy drinks) on the day of treatment, if possible, as they may cause dehydration

The same discussion also raised a broader supply chain point: if a small number of upstream manufacturers supply most downstream labs and vendors, then a single finishing-stage issue could propagate across multiple brands

Two preliminary randomized controlled trials indicated that supplementation with large doses of choline or betaine decreased plasma homocysteine levels in healthy men and CVD patients