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Contraindications Given the limited safety data, conservative contraindications would include pregnancy or plans to become pregnant, breastfeeding, age under 18, severe liver or kidney disease, and any condition requiring medications with unknown interaction potential

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Safe B12 Dosage and NHS Recommendations The NHS and UK health authorities provide clear guidance on appropriate vitamin B12 intake, emphasising that most people obtain sufficient amounts through diet alone

NAD+ repletion improves mitochondrial and stem cell function and enhances life span in aged mice

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Early treatment is essential as delayed therapy can result in incomplete recovery or permanent damage