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Comprehensive packages including regular consultations, nutritional counselling, exercise guidance, and psychological support cost more but may improve outcomes

Injection day eating Most semaglutide users find that appetite suppression peaks within 24 to 48 hours after injection

Allergic reactions, though rare with FDA-approved semaglutide, may present as rash, swelling of the mouth or throat, or difficulty breathingthis requires emergency care

Most patients use it for several months, tapering off once goals are met or transitioning to a maintenance dose

doi: 10.1038/s41419-018-0468-2 48 ChenS.SayanaP.ZhangX.LeW

The injections should be done on the same day each week, at any time of the day, with or without meals