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Indeed, VPA promotes the transport of glutamine through the mitochondrial membrane, thereby enhancing glutaminase activity

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In addition, melatonin is a potent free radical scavenger and an antioxidant targeted at the mitochondria, thereby protecting against oxidative stress and locally reducing reactive oxygen species (ROS) and reactive nitrogen species (RNS) [3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21]

Spectrochim Acta Part A Mol Biomol Spectrosc 118:776781 Jiang Z, Zhou L, Liang A (2011) Resonance scattering detection of trace melamine using aptamer-modified nanosilver probe as catalyst without separation of its aggregations

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