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Nat Genet 2002

Modulation of CPT-1 may affect energy metabolism and food intake, and research is ongoing into the effects of both stimulation and inhibition of CPT-1 and in relation to obesity management [74]

Rather than triggering GLP-1 and GIP production in the body, the supplement mimics these hormones but is not broken down so quickly by the enzyme DPP-4, which starts breaking down naturally-produced GLP-1 within minutes

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The findings, published in JAMA Network Open , suggest that medication changes are not uncommon among patients undergoing weight loss and that clinicians should encourage them to change GLP-1RAs if necessary to promote continuity of care

Eating five to six small meals throughout the day may feel more manageable than three larger ones