Antituberculosis drugs (HRZE) cause gut microbiota dysbiosis, particularly reducing the abundance of probiotics such as Lactobacillus , which is negatively correlated with liver injury markers (e.g., AST, ALT) ( Lactobacillus
This is especially critical in the lungs, since the lungs are particularly sensitive to the effects of both oxidation and inflammation
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Future surveillance frameworks should prioritize multinational data harmonization and integration with real-world evidence streams to enhance validity
In addition, GLP-1s have the potential to impact substance or alcohol use disorder and Prader-Willi syndrome through their effect on satiety hormones
However, research showed that GLP-1 was removed from our bloodstream quickly and had a half-life of two minutes as its degraded by an enzyme called DPP4
