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Figure 2 3.4.1 Probiotics impact on innate immune response Probiotics, especially Lactobacillus, have been shown to be able to attain the remarkable capability of enhancing neutrophil functionality by secreting exopolysaccharides (EPS) that activate the TLR2/MyD88 signaling pathway, thereby facilitating chemotaxis and phagocytosis

This study demonstrates that DHHC9-mediated S-palmitoylation of glucose transporter GLUT1 promotes glycolysis in human GBM cells, implying that S-palmitoylation-regulated membrane localization of cellular proteins may be required for metabolic reprogramming in cancer cells

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