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So there's a lot of nuance here
Baseline biomarker assessment can guide titration
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Additionally, Pt II -01 interacted with CT-DNA and 5-GMP, indicating the formation of platinum(II)-linked DNA adducts upon exposure to visible light
Because studies are conducted at different times, with different samples of patients, by different investigators, employing different criteria and/or different interpretations of the same criteria, under different conditions (dose, dosing regimen, etc.), quantitative estimates of treatment response and the timing of response may be expected to vary considerably from study to study
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