It's a meal structure issue
Patients typically experience reductions in HbA1c (glycated haemoglobin) of approximately 1.01.5% (1116 mmol/mol) when added to existing therapy, with some agents achieving even greater reductions
It helps improve insulin sensitivity, supports energy production, and enhances metabolic efficiency
What are glitazones
Additional genome-wide association analysis involving 61,488 coronary artery disease patients and 163,728 controls found that the variant at rs10305492 in GLP1R is significantly associated with reduced risk of coronary artery disease, independent of the effect on reduced fasting glucose
Even 4 mg weekly improved fasting glucose, insulin sensitivity, and HbA1c, showing that metabolic benefits can appear before maximum weight-loss effects