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Taken together, all results observed in mentioned studies indicate a new underlying mechanism of mechanical overloading to the progression of OA, that is, the GPX4-associated ferroptosis pathway (Fig

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However, as the DTSQc was created in response to limitations of the DTSQs, it may be reasonable to suggest that the DTSQs stands as a reliable HRQoL questionnaire

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The combined quinone redox glutathione metabolism model can be used to simulate experimentally challenging scenarios such as potential redox cycling toxicity, while providing a platform from which quinone exposure and concentration toxicity experiments may be guided