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This rapid depletion isn't just a temporary setback

9 The scope of this opinion paper is limited to GLP-1RA therapy and other antidiabetic agents with CV benefits are excluded

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doi:10.3390/jcm12010145 PubMed PMID: 36614945

Severe signs requiring medical attention include persistent vomiting or diarrhea, confusion, rapid heart rate, and significant lightheadedness when standing