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FIGURE 2 An umbrella review of meta-analyses of observational studies archived in the PubMed and Embase databases that included 1,175,720 women who had used antidepressants during pregnancy reported that the use of SSRIs during pregnancy was associated with a 43% increase in the risk of preterm labor, a 43% increased risk of respiratory distress, a 33% associated with respiratory distress, a 26% increased risk of cardiovascular malformations, and a decrease in 1-min Apgar scores (Vlenterie et al

PL, the SAE rates were 34.1% with dapagliflozin and 36.2% with PL over a median of 4.2 years [14]

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A similar pattern was observed in the combination-treatment study

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, , ( [] : -1,93 [0,12] / -1,90 [0,12] / , =0,83) (-2,56 [0,09] / -2,43 [0,09] / , =0,26)