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doi: 10.2337/dc25-S013 37 DasSREverettBMBirtcherKKBrownJMJanuzziJLKalyaniRRet al

However, robust randomized controlled trials specifically in RA populations remain limited, and current evidence does not support GLP-1 drugs as monotherapy for RA

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Protein Aim for 1.21.6 g/kg of body weight per day Spread protein intake across meals to maximise muscle retention Combine with 23 resistance-training sessions per week While all movement is beneficial, lifting progressively heavier weights provides the stimulus needed to preserve muscle mass and bone density

In summary: Evaluating SMM loss plausibly due to GLP-1 medications compared to weight loss through other interventions (without GLP-1 medications), we find a dearth of evidence of disproportionate muscle mass loss

Nutrients 12 (11), 3517