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One open-label pilot study (Honda et al., PMC5548760, n=29 NAFLD patients) found that 300 mg/day reduced ALT and liver fat markers, but this was a clinical population without a control group

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Similarly, Prostaglandin E1 pretreatment increases the protein level of HIF-1 in MSCs, which reduces MSCs apoptosis and enhances the protein levels of CXCR4, MSCs migration, and VEGF secretion

thus, the ratio of GSH to GSSG is used as an indicator of oxidative stress

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