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doi: 10.1159/000478872

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Persistent activation of the hypothalamic-pituitary-adrenal (HPA) axis, the bodys primary neuroendocrine stress-response system, has been linked to anxiety, depression, fatigue, cognitive impairment, metabolic dysfunction, cardiovascular disease, and accelerated biological aging [15]

Keep in mind, though, that this is based on results from rodent studies, so its still unclear whether these medications contribute to thyroid tumors in humans

If you have low levels of vitamin B12, you may experience sensations such as numbness or tingling in the hands, legs, or feet, difficulty walking caused by problems with balance, or having an inflamed, swollen tongue

Wetzler M, Talpaz M, Yee G, Stass SA, Van Etten RA, Andreeff M , Goodacre AM, Kleine HD, Mahadevia RK, Kurzrock R