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With increasing stress and exposure to pollution, glutathione is depleting in human bodies faster than it did in previous generations, even as early as our 20s

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Nsengimana et al

[DOI] [PubMed] [Google Scholar] 129.Horowitz J.D., Henry C.A., Syrjanen M.L., Louis W.J., Fish R.D., Smith T.W., Antman E.M

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The TRIB3 is induced in DR under ERS, leading to overexpression of HIF1