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This genotype-dependent efficacy is robustly supported by epidemiological and clinical evidence in colorectal cancer, particularly for individuals with combined GSTM1 and GSTT1 null genotypes

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Last reviewed: May 23, 2026 Last updated: May 23, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations