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However, knocking out FAP expressing fibroblasts in mice did not suppress inflammation but reduced the extent of tissue damage, confirming the pathogenic role of FAP in arthritis

433 Moreover, it has also been documented that p300 in association with CREB suppress lipid peroxidation by binding to the GPX4 (glutathione peroxidase 4) promoter region, which further inhibits ferroptosis in lung adenocarcinoma

This uncertainty may reflect limitations in statistical power, particularly for MR-Egger, which requires stronger assumptions and larger sample sizes to detect causal effects

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